by frotes
I think in the first 2 rounds (probably even 3rd), I would go for knowledge. The reason is because then you would have +3K and if you pick up the +1k/+1c tile, that sets you up for +4K a turn for the rest of the game.Hitting the 4K break point every round is more important than the Net income of the resources throughout the game because you can snowball the early game into a better late game.
If you build a late game Acad, then I would probably get QIC as it is more likely for me to use it for QIC actions. In fact would I consider QIC Acad more for using the QIC to get onto early gaia planets or for range, rather than for 4QIC to get tech. Unless I was getting QICs another way and it would be more likely for me to get 4 in round 2-3